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Welcome. This is the Prometheus website for LOTRONEX® — a medication that treats pain, urgency, and frequency of bowel movements in women with severe diarrhea-predominant irritable bowel syndrome (D-IBS). Whether you're a patient, physician, or pharmacist, LOTRONEX.com is your online resource for severe D-IBS and treatment with LOTRONEX.
Simply click the above image to learn more about LOTRONEX.
INDICATION: LOTRONEX is indicated only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) who have: chronic IBS symptoms (generally lasting 6 months or longer), had anatomic or biochemical abnormalities of the gastrointestinal tract excluded, and not responded adequately to conventional therapy. Diarrhea-predominant IBS is severe if it includes diarrhea and one or more of the following: frequent and severe abdominal pain/discomfort, frequent bowel urgency or fecal incontinence, disability or restriction of daily activities due to IBS. Because of infrequent but serious gastrointestinal adverse events associated with LOTRONEX, the indication is restricted to those patients for whom the benefit-to-risk balance is most favorable. Clinical studies have not been performed to adequately confirm the benefits of LOTRONEX in men.
Please consult the Complete Prescribing Information.
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