Efficacy Information

The Most Bothersome IBS Symptoms for Patients^1*

*Nonconstipated females.

LOTRONEX Provides Relief:

Pain and Discomfort
Patients report relief from pain and discomfort after 12 weeks of use with LOTRONEX.

Adequate Relief Rate of IBS Pain and Discomfort Over 12 Weeks Stratified by Increasing Severity of Baseline Abdominal Pain—Integrated Analysis from 6 Studies Involving D-IBS Patients²

Urgency
Patients report satisfactory control of bowel urgency after 12 weeks of use with LOTRONEX.

PRIMARY ENDPOINT
Proportion of Days Subjects Reported Satisfactory Control of Bowel Urgency in Patients with Severe D-IBS³

Frequency
Patients report fewer stools per day after 12 weeks of use with LOTRONEX.

FREQUENCY
Median Stools Per Day by Week in Patients With Severe D-IBS²

Some patients experienced serious complications of constipation or ischemic colitis without warning.

Please consult the Complete Prescribing Information.