Welcome to the Physician Home Page at LOTRONEX.com!

In this section, you will find information about LOTRONEX^® that can help you understand which patients may be appropriate for treatment with LOTRONEX.

To help identify patients who may be severely affected by D-IBS, you may wish to discuss the effect of their symptoms on their daily life by using the following checklist:
  Have your patients refrained from travel?
  Have your patients avoided participating in family functions?
  Have your patients planned their days around access to a bathroom?
  Have you asked your patients what compromises they have made?

To learn more, just click on any one of the buttons to the left.

Only physicians who enroll in the Prescribing Program for LOTRONEX^TM should prescribe LOTRONEX.

INDICATION: LOTRONEX is indicated only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) who have: chronic IBS symptoms (generally lasting 6 months or longer), had anatomic or biochemical abnormalities of the gastrointestinal tract excluded, and not responded adequately to conventional therapy. Diarrhea-predominant IBS is severe if it includes diarrhea and one or more of the following: frequent and severe abdominal pain/discomfort, frequent bowel urgency or fecal incontinence, disability or restriction of daily activities due to IBS. Because of infrequent but serious gastrointestinal adverse events associated with LOTRONEX, the indication is restricted to those patients for whom the benefit-to-risk balance is most favorable. Clinical studies have not been performed to adequately confirm the benefits of LOTRONEX in men.

Please consult the Complete Prescribing Information.